Director, Enterprise Infrastructure Engineering & Operations

This position is listed on behalf of a partner company, who manages all applications and next steps. Our partner is looking for a Director, Enterprise Infrastructure Engineering & Operations based in the United States.

• Define and execute enterprise infrastructure and modern workplace roadmaps, architecture standards, technology lifecycle plans, and modernization strategies spanning AWS, Microsoft 365, identity, endpoints, networking, compute, storage, backup, recovery, and monitoring.
• Act as a hands-on technical leader by designing, configuring, automating, implementing, and troubleshooting complex infrastructure solutions using PowerShell, Microsoft Graph, Infrastructure as Code, and other relevant technologies.
• Lead high-risk technical decisions, major infrastructure changes, escalations, and initiatives while improving platform reliability, security, scalability, performance, automation, cost efficiency, disaster recovery, and operational resilience.
• Establish engineering, configuration, documentation, testing, monitoring, identity, endpoint, Zero Trust, information protection, and lifecycle standards in collaboration with cybersecurity, risk, and quality stakeholders.
• Lead, coach, and develop infrastructure engineers while overseeing service desk operations, managed service providers, and vendors through clear ownership models, service levels, performance metrics, escalation processes, and accountability.
• Partner with application, data, AI, security, quality, and business teams to translate organizational requirements into secure, scalable, supportable technology platforms and ensure effective implementation and operational handoff.
• Manage infrastructure budgets, forecasts, cloud consumption, Microsoft licensing, contracts, vendor relationships, capacity planning, technical debt, and investment priorities.
• Communicate technology roadmaps, service performance, operational risks, dependencies, and strategic trade-offs to both technical teams and executive stakeholders.

• Bachelor’s degree in Information Technology, Computer Science, Engineering, or a related discipline, or an equivalent combination of education and relevant professional experience.
• 15+ years of progressive experience across enterprise infrastructure, platform engineering, AWS and Microsoft cloud technologies, modern workplace platforms, and technology operations.
• 7+ years of experience leading technical teams and enterprise platform capabilities, with demonstrated success balancing hands-on engineering with people and operational leadership.
• Proven experience managing people, vendors, budgets, technology roadmaps, and enterprise operational outcomes.
• Strong expertise in AWS infrastructure and Microsoft technologies including Microsoft 365, Entra ID, Exchange Online, Teams, SharePoint Online, OneDrive, Intune, Microsoft Defender, Microsoft Purview, and Microsoft Graph.
• Deep knowledge of Azure and hybrid cloud architecture, enterprise networking, identity and endpoint engineering, virtualization, storage, backup and recovery, business continuity, scripting, automation, Infrastructure as Code, configuration management, and monitoring.
• Experience with Zero Trust, conditional access, identity governance, privileged access, endpoint security, secure cloud configuration, regulated-system controls, IT service management, incident and problem management, change management, service levels, and managed service performance.
• Experience in biotechnology, pharmaceutical, life sciences, healthcare, or another regulated industry is strongly preferred; exposure to GxP environments is an advantage.
• Strong communication, coaching, stakeholder management, vendor management, negotiation, prioritization, and decision-making skills, with sound judgment around internal development, managed services, automation, and external expertise.
• Ability to work collaboratively in a fast-paced environment and demonstrate values centered on courage, community, patient focus, and teamwork.
• Ability to travel approximately 15–30% and work onsite or face-to-face with colleagues in San Diego as needed; this is not a fully remote position.

• Target base salary range of $189,000–$246,000, with actual compensation determined by experience, education, skills, location, and other relevant factors.
• Cash compensation combining base salary and short-term incentive opportunities.
• Long-term incentive compensation through company stock opportunities.
• Premium health, financial, work-life, and wellbeing benefits for eligible employees and dependents.
• Medical and related health coverage, life insurance, and disability benefits.
• Retirement plan with employer matching.
• Generous paid time off.
• Wellness and employee support programs.
• Opportunities to work with modern cloud, infrastructure, automation, security, and AI technologies.